Endocrine Abstracts

Introduction: The effect of aldosterone levels on the severity of arterial hypertension was established in many studies. Changes in the level of aldosterone can lead to disorders of the cardiovascular, nervous, excretory systems. One of the factors affecting the fluctuation of aldosterone is the presence of adrenal gland mass.Aim: To check for a correlation between the identified adrenal masses and the severity of arterial hypertension against the backgr...

Introduction: SARS-COV-2 is a new infection with little known consequences. As data accumulated, it became known that the thyroid gland is also affected as a result of infection. During the reconvalescence period, some patients developed severe thyrotoxicosis, which did not have the classic clinical picture of subacute thyroiditis or autoimmune.Aim: To study the course of subacute thyroiditis in patients after infection with COVID-19.<p class="abstex...

The article is devoted to one of the most pressing medical problems – diabetes mellitus type 2.Objective: To study the peculiarities of the course of diabetes mellitus type 2 in persons over 65 years of age; to evaluate the effectiveness of different therapy regimens for the level of HbA1C.Material and methods: The retrospective study included 100 patients with type 2 diabetes (T2D). The age of the patients: 65 to 82 years. Th...

Introduction: Glutathione system prevents oxidative stress development in erythrocites. When this system becomes depressed it predisposes a cell to apoptosis.Aim: To study glutathione system status in patients with diabetesMaterials and methods: Included patients were divided into four groups: group 1–41 almost healthy person (control group), group 2–41 patients with type 2 diabetes (T2D), group 3–40 patients with T2...

Introduction: Glutathione system prevents oxidative stress development in erythrocites. When this system becomes depressed it predisposes a cell to apoptosis.Aim: To study glutathione system status in patients with diabetesMaterials and methods: Included patients were divided into four groups: group 1–41 almost healthy person (control group), group 2–41 patients with type 2 diabetes (T2D), group 3–40 patients with T2...

Introduction: The presence of diabetes-associated antibodies is an indicator of β-cell destruction. Our goal was to find out the prevalence of autoantibodies associated with the new onset of type 1 diabetes mellitus (DM1) without family history.Subjects and Methods: 22 patients (10 women and 12 men) with newly diagnosed DM1 no family history were examined. Average age of patients was 31.7&pm;7.3 y.o., experience of DM1 was 2.3&pm;0.8 months. All the...

It is known that presence of certain genetic polymorphism plays important role in development of chronic complications in patients with type 2 diabetes (T2D).Aim: To analyze distribution of VEGF G/C polymorphisms and PAI-1 4G/5G polymorphisms in patients with T2D and IHD.Materials and methods: The following groups of studies were formed: 1 – 24 almost healthy people; 2 – 28 patients with prediabetes; 3 – 37 patients ...

Neutrophil gelatinase-associated lipocalin (NGAL) was shown to be highly useful in assessing kidney injury in patients with diabetic nephropathy. Taking into account recent data that dysthyroidism may have reversible effects on GFR the purpose of the study was to investigate potential relationship between serum NGAL levels, thyroid status and ultrasound thyroid characteristics in patients with type 1 diabetes (T1D) with CKD.Materials and methods: We recr...

Neutrophil gelatinase-associated lipocalin (NGAL) was shown to be highly useful in assessing kidney injury in patients with diabetic nephropathy. Taking into account recent data that dysthyroidism may have reversible effects on GFR the purpose of the study was to investigate potential relationship between serum NGAL levels, thyroid status and ultrasound thyroid characteristics in patients with type 1 diabetes (T1D) with CKD.Materials and methods: We recr...

Rationale: Obesity, prediabetes and diabetes are strongly associated with microcirculation (MC) abnormalities. It is known that pathological changes in microvessels predispose to CHD, CKD and retinopathy. Also it is widely recognized that biochemical and immunological changes accompanied with obesity and overweight lead to MC damage.ObjectiveOf the study was to assess changes in MC in patients with overweight and obesity.<p cla...